Clonazepam Side Effects Weight Gain
Search for: Clonazepam Side Effects Weight Gain
Weight Loss and ClonazepamWeight Gain and Klonopin
Klonopin Weight Loss
Does Klonopin Cause Weight Loss
Can Clonazepam Cause Weight Loss
Clonazepam Weight Gain or Loss
How Skinny Woman Gain Weight
Need to Gain Weight
Clonazepam Maximum Daily Dose
All
Clonazepam
Adverse Eventn = 96n = 129n = 113n = 235N = 574N = 294
by Body System%%%%%%
Central & Peripheral Nervous System
Somnolence†263550363710
Dizziness5512884
Coordination Abnormal†127960
Ataxia†218850
Dysarthria†004320
Psychiatric
Depression768871
Memory Disturbance252542
Nervousness143432
Intellectual Ability Reduced024320
Emotional Lability012211
Libido Decreased013110
Confusion022110
Respiratory System
Upper Respiratory Tract Infection†10107684
Sinusitis428443
Rhinitis324221
Coughing224020
Pharyngitis113221
Bronchitis102211
Gastrointestinal System
Constipation†015322
Appetite Decreased110311
Abdominal Pain†222011
Body as a Whole
Fatigue967774
Allergic Reaction314221
Musculoskeletal
Myalgia214011
Resistance Mechanism Disorders
Influenza325543
Urinary System
Micturition Frequency122110
Urinary Tract Infection†002210
Vision Disorders
Blurred Vision123011
Reproductive Disorders‡
Female
Dysmenorrhea065232
Colpitis402111
Male
Ejaculation Delayed002210
Impotence302110
Commonly Observed Adverse Events Table 4: Incidence of Most Commonly Observed Adverse Events* in Acute Therapy in Pool of 6 to 9 Week Trials*
Treatment-emergent events for which the incidence in the Clonazepam patients was ? 5% and at least twice that in the placebo patients.
Adverse EventClonazepam (N = 574)Placebo (N = 294)
Somnolence37%10%
Depression7%1%
Coordination Abnormal6%0%
Ataxia5%0%
Treatment-Emergent Depressive Symptoms
In the pool of two short-term placebo-controlled trials, adverse events classified under the preferred term “depression” were reported in 7% of Clonazepam-treated patients compared to 1% of placebo-treated patients, without any clear pattern of dose relatedness. In these same trials, adverse events classified under the preferred term “depression” were reported as leading to discontinuation in 4% of Clonazepam-treated patients compared to 1% of placebo-treated patients. While these findings are noteworthy, Hamilton Depression Rating Scale (HAM-D) data collected in these trials revealed a larger decline in HAM-D scores in the Clonazepam group than the placebo group suggesting that Clonazepam-treated patients were not experiencing a worsening or emergence of clinical depression.
Other Adverse Events Observed During the Premarketing Evaluation of Clonazepam in Panic Disorder
Following is a list of modified CIGY terms that reflect treatment-emergent adverse events reported by patients treated with Clonazepam at multiple doses during clinical trials. All reported events are included except those already listed in Table 3 or elsewhere in labeling, those events for which a drug cause was remote, those event terms which were so general as to be uninformative, and events reported only once and which did not have a substantial probability of being acutely life-threatening. It is important to emphasize that, although the events occurred during treatment with Clonazepam, they were not necessarily caused by it.
Events are further categorized by body system and listed in order of decreasing frequency. These adverse events were reported infrequently, which is defined as occurring in 1 100 to 1 1000 patients.
Body as a Whole: weight increase, accident, weight decrease, wound, edema, fever, shivering, abrasions, ankle edema, edema foot, edema periorbital, injury, malaise, pain, cellulitis, inflammation localized
Cardiovascular Disorders: chest pain, hypotension postural
Central and Peripheral Nervous System Disorders: migraine, paresthesia, drunkenness, feeling of enuresis, paresis, tremor, burning skin, falling, head fullness, hoarseness, hyperactivity, hypoesthesia, tongue thick, twitching
Gastrointestinal System Disorders: abdominal discomfort, gastrointestinal inflammation, stomach upset, toothache, flatulence, pyrosis, saliva increased, tooth disorder, bowel movements frequent, pain pelvic, dyspepsia, hemorrhoids
Hearing and Vestibular Disorders: vertigo, otitis, earache, motion sickness
Heart Rate and Rhythm Disorders: palpitation
Metabolic and Nutritional Disorders: thirst, gout
Musculoskeletal System Disorders: back pain, fracture traumatic, sprains and strains, pain leg, pain nape, cramps muscle, cramps leg, pain ankle, pain shoulder, tendinitis, arthralgia, hypertonia, lumbago, pain feet, pain jaw, pain knee, swelling knee
Platelet, Bleeding and Clotting Disorders: bleeding dermal
Psychiatric Disorders: insomnia, organic disinhibition, anxiety, depersonalization, dreaming excessive, libido loss, appetite increased, libido increased, reactions decreased, aggressive reaction, apathy, attention lack, excitement, feeling mad, hunger abnormal, illusion, nightmares, sleep disorder, suicide ideation, yawning
Reproductive Disorders, Female: breast pain, menstrual irregularity
Reproductive Disorders, Male: ejaculation decreased
Resistance Mechanism Disorders: infection mycotic, infection viral, infection streptococcal, herpes simplex infection, infectious mononucleosis, moniliasis
Respiratory System Disorders: sneezing excessive, asthmatic attack, dyspnea, nosebleed, pneumonia, pleurisy
Skin and Appendages Disorders: acne flare, alopecia, xeroderma, dermatitis contact, flushing, pruritus, pustular reaction, skin burns, skin disorder
Special Senses Other, Disorders: taste loss
Urinary System Disorders: dysuria, cystitis, polyuria, urinary incontinence, bladder dysfunction, urinary retention, urinary tract bleeding, urine discoloration
Vascular (Extracardiac) Disorders: thrombophlebitis leg
Vision Disorders: eye irritation, visual disturbance, diplopia, eye twitching, styes, visual field defect, xerophthalmia
Top
Side Effects by Body System - for Healthcare Professionals
Nervous system
Nervous system side effects are common, particularly at the initiation of therapy and include drowsiness, fatigue, ataxia, confusion, depression, daytime anxiety, and amnesia. Nystagmus, diplopia, vertigo, headache, respiratory depression, tremor and slurred speech have also been reported less frequently.
Sedation may initially occur in up to 50% of treated patients. Ataxia may occur in 30% of patients. Five to 6% of patients treated with clonazepam for seizures may develop more frequent seizures or a new type of seizure disorder. Weakness and hypotonia have also been reported. A case report has suggested that clonazepam may induce Tourette s syndrome.
Psychiatric
Behavioral problems have been reported in as many as 30% of treated patients.
Psychiatric side effects have been reported and include behavioral disinhibition (particularly sexual disinhibition), depression, and rarely, psychosis and mania.
Other
Other side effects have included withdrawal symptoms (similar to those which may occur after withdrawal of barbiturates and alcohol) which have been reported after abrupt cessation of clonazepam. Specifically, seizures, agitation, restlessness, anxiety, delirium, psychosis, dysphoria, insomnia, tremor, abdominal cramps, vomiting, rash, and sweating have been reported to have occurred, especially after long-term therapy.
Genitourinary
In one study, anorgasmia occurred in 44% of patients treated with clonazepam while anorgasmia occurred in only 6% of patients treated with placebo.
Genitourinary side effects may include urinary incontinence, anorgasmia, ejaculatory delay, and erectile dysfunction.
Hematologic
Hematologic side effects including thrombocytopenia have been reported rarely.
Gastrointestinal
Gastrointestinal side effects including hypersalivation, diarrhea, constipation, nausea, increased appetite, and anorexia have been reported.
Respiratory
Respiratory side effects including bronchial hypersecretion have been reported.
Dermatologic
Dermatologic side effects have included cases of rashes associated with clonazepam therapy. A case of erythema multiforme associated with clonazepam therapy has also been reported.
Ocular
Weight Loss and Clonazepam
Weight Gain and Klonopin
Klonopin Weight Loss
Does Klonopin Cause Weight Loss
Can Clonazepam Cause Weight Loss
Clonazepam Weight Gain or Loss
How Skinny Woman Gain Weight
Need to Gain Weight
Search for: Clonazepam Side Effects Weight Gain
Kambing Boer foto paha bugil